Waiting
Traitement de la connexion…

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Developmental Biology / Mosaic Zebrafish Transgenesis for Functional…
JoVE Journal
Developmental Biology

Un abonnement à JoVE est nécessaire pour afficher ce contenu. Connectez-vous ou commencez votre essai gratuit.

JoVE Journal Developmental Biology
Mosaic Zebrafish Transgenesis for Functional Genomic Analysis of Candidate Cooperative Genes in Tumor Pathogenesis
 

Mosaic Zebrafish Transgenesis for Functional Genomic Analysis of Candidate Cooperative Genes in Tumor Pathogenesis

Article DOI: 10.3791/52567-v • 09:45 min • March 31st, 2015
March 31st, 2015 •
1, 2, 3, 3, 1,3
1Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic College of Medicine, Center for Individualized Medicine, 2Tufts University School of Medicine, 3Department of Biochemistry and Molecular Biology, Mayo Clinic

Chapitres

résumé
Automatic Translation

The goal of this study is to demonstrate how the mosaic transgenesis strategy can be used in zebrafish to rapidly and efficiently assess the relative contributions of multiple oncogenes in tumor initiation and progression in vivo.

Tags

Keywords: Mosaic Zebrafish Transgenesis Functional Genomics Tumor Pathogenesis Cooperative Genes ALK MYCN Neuroblastoma Cancer Model In Vivo Imaging Transgenic Techniques
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter