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Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction
 

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction

Article DOI: 10.3791/54021-v • 14:19 min • October 14th, 2016
October 14th, 2016 •
1, 1,2, 1,2, 2,4, 1,3, 1,3
1Department of Experimental Cardiology, University Medical Center Utrecht, 2Department of Cardiology, University Medical Center Utrecht, 3Department of Clinical Chemistry and Hematology, University Medical Center Utrecht, 4Interuniversity Cardiology Institutes of the Netherlands (ICIN)

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Reliable and accurate outcome assessment is the key for translation of preclinical therapies into clinical treatment. The current paper describes how to assess three clinically relevant primary outcome parameters of cardiac performance and damage in a pig acute myocardial infarction model.

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Keywords: Acute Myocardial Infarction Pig Model Primary Outcome Assessment Ischemia Reperfusion Injury Cardiac Remodeling 3D Transesophageal Echocardiography Pressure-volume Loop Measurements Infarct Size Area At Risk Staining
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