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Generasjon av menneskelig 3D lungevev kulturer (3D-LTCs) for sykdom modellering
 
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Generasjon av menneskelig 3D lungevev kulturer (3D-LTCs) for sykdom modellering

Article DOI: 10.3791/58437-v • 05:47 min • February 12th, 2019
February 12th, 2019 •
1,2,3, 4,5,6, 4,5,6, 2,7, *1,2,3, *1,2,3,8
1Comprehensive Pneumology Center, Ludwig-Maximilians-Universität and Helmholtz Zentrum Munich, 2German Center of Lung Research (DZL), 3Translational Lung Research and CPC-M bioArchive, Helmholtz Zentrum München, Comprehensive Pneumology Center Munich DZL/CPC-M, 4Department of Experimental Medical Science, Lung Bioengineering and Regeneration, Lund University, 5Wallenberg Center for Molecular Medicine, Lund University, 6Stem Cell Centre, Lund University, 7Asklepios Fachkliniken Munich-Gauting, 8Department of Medicine, Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado
* These authors contributed equally

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Her presenterer vi en protokoll forberedelse til agarose-fylt menneskelige presisjonsstyrte kutte lunge skiver fra resected pasienten vev som er egnet for å generere 3D lunge vev kulturene modell menneskelige lungesykdommer i biologiske og biomedisinsk studier.

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Medisin problemet 144 3D vev kultur ex-vivo vev kultur presisjonsstyrte kutte lunge skiver PCLS 3D-LTCs lungesykdom sykdom dyremodeller menneskelige ex-vivo modeller lunge fibrosis
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