Waiting
Traitement de la connexion…

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Cancer Research / A Human Peripheral Blood Mononuclear Cell (PBMC)…
JoVE Journal
Cancer Research

Un abonnement à JoVE est nécessaire pour afficher ce contenu. Connectez-vous ou commencez votre essai gratuit.

JoVE Journal Cancer Research
A Human Peripheral Blood Mononuclear Cell (PBMC) Engrafted Humanized Xenograft Model for Translational Immuno-oncology (I-O) Research
 

A Human Peripheral Blood Mononuclear Cell (PBMC) Engrafted Humanized Xenograft Model for Translational Immuno-oncology (I-O) Research

Article DOI: 10.3791/59679-v • 08:17 min • August 15th, 2019
August 15th, 2019 •
*1, *1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1
1BeiGene (Beijing) Co., Ltd.
* These authors contributed equally

Chapitres

résumé
Automatic Translation

We describe a human peripheral blood mononuclear cell (PBMC) — based humanized xenograft mouse model for translational immuno-oncology research. This protocol could serve as a general guideline for establishing and characterizing similar models for I-O therapy assessment.

Tags

Keywords: PBMC Humanized Xenograft Immuno-oncology Myeloid Cell Depletion Cyclophosphamide Disulfiram Tumor Growth Immunohistochemistry Antigen Retrieval
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter