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Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research
 

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control

Article DOI: 10.3791/63921-v • 05:41 min • December 16th, 2022
December 16th, 2022 •
1, 2,3,4,5, 5,6, 5,7
1Department of Life Science, Fu Jen Catholic University, 2Department of Medicine, MacKay Medical College, 3Department of Emergency Medicine, MacKay Memorial Hospital, 4Graduate Institute of Injury Prevention and Control, Taipei Medical University, 5MacKay Junior College of Medicine, Nursing, and Management, 6Division of Cardiology, Department of Internal Medicine, Taitung Mackay Memorial Hospital, 7Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, MacKay Memorial Hospital

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Herein, we present a protocol focusing on the quality control of the left anterior descending coronary artery ligation by technically modifying the traditional procedure in rats for acute myocardial ischemia-reperfusion research.

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Keywords: Ischemia-reperfusion Left Anterior Descending Coronary Artery Ligation Rat Model Thoracotomy Surgical Procedure Tissue Preparation Cotton Balls Holding Hooks Ligation Loop Snare Loop Controller Anesthesia Endotracheal Intubation Rib Resection Surgical Window Pericardium Exposure
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