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Single Molecule Methods for Monitoring Changes in Bilayer Elastic Properties
 
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Single Molecule Methods for Monitoring Changes in Bilayer Elastic Properties

Article DOI: 10.3791/1032-v • 12:21 min • November 3rd, 2008
November 3rd, 2008 •
1, 2, 2, 2
1Department of Physiology and Biophysics, Weill Cornell Medical College, 2Department of Physiology and Biophysics, Weill Cornell Medical College of Cornell University

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Membrane protein function is regulated by the cell membrane lipid composition. This video-article details how to form a patch using bilayer patch electrodes, as well as how to use gramicidin channels as reporters of altered membrane properties.

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Single Molecule Methods Monitoring Changes Bilayer Elastic Properties Membrane Protein Function Cell Membrane Lipid Composition Lipid-protein Interactions Lipid Bilayer-protein Interactions Pharmacological Research Pharmaceuticals Lipid Bilayer Material Properties Altered Membrane Protein Function Gramicidin Channels Conformational Changes Gramicidin Subunits Properties Of The Lipid Gramicidin Channel Current Reporter Compounds
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