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The Generation of Closed Femoral Fractures in Mice
 

The Generation of Closed Femoral Fractures in Mice: A Model to Study Bone Healing

Article DOI: 10.3791/58122-v • 05:53 min • August 16th, 2018
August 16th, 2018 •
1, 1, 1, 1
1Department of Anatomy and Cell Biology, Indiana University School of Medicine

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The murine closed femoral fracture model is a powerful platform to study fracture healing and novel therapeutic strategies to accelerate bone regeneration. The goal of this surgical protocol is to generate unilateral closed femoral fractures in mice using an intramedullary steel rod to stabilize the femur.

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Keywords: Closed Femoral Fracture Bone Healing Mouse Model Surgical Procedure Minimally Invasive Standardized Fracture Three-point Bending Fracture Geometry Fracture Healing Research
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