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A Surgical Model of Heart Failure with Preserved Ejection Fraction in Tibetan Minipigs
 

A Surgical Model of Heart Failure with Preserved Ejection Fraction in Tibetan Minipigs

Article DOI: 10.3791/63526-v • 07:09 min • February 18th, 2022
February 18th, 2022 •
*1,2, *1,3, *1, *1, 2, 1, 1, 1, 1
1Guangdong Laboratory Animals Monitoring Institute, 2Department of Cardiovascular Surgery, the First Affiliated Hospital, Jinan University, 3College of Veterinary Medicine, South China Agricultural University
* These authors contributed equally

Capitoli

Riepilogo
Automatic Translation

The present protocol describes a step-by-step procedure to establish a minipig model of heart failure with preserved ejection fraction using descending aortic constriction. The methods for evaluating cardiac morphology, histology, and function of this disease model are also presented.

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Keywords: Heart Failure HFpEF Tibetan Minipigs Surgical Model Aortic Constriction Pressure Overload Echocardiography Animal Care Surgical Technique Anesthesia Monitoring
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