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Mouse Embryonic Lung Culture, A System to Evaluate the Molecular Mechanisms of Branching
 

Mouse Embryonic Lung Culture, A System to Evaluate the Molecular Mechanisms of Branching

Article DOI: 10.3791/2035-v • 07:32 min • June 30th, 2010
June 30th, 2010 •
1, 1, 1
1Saban Research Institute, Childrens Hospital Los Angeles

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Early embryonic lung organ culture is a very useful system to study epithelial-mesenchymal interactions. Both epithelial and mesenchymal morphogenesis proceeds under specific conditions that can be readily manipulated in this system.

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Mouse Embryonic Lung Culture Molecular Mechanisms Branching Lung Primordial Specification Branching Morphogenesis Pulmonary Cell Lineages Lung Endoderm Surrounding Mesenchyme Mesothelium Inductive Signals Epithelial-mesenchymal-mesothelial Interactions Embryonic Lung Organ Culture Epithelial-mesenchymal Interactions Serumless Culture Media Gain Of Function Loss Of Function Expressed Proteins Recombinant Viral Vectors Transgenic Mouse Strains Antisense RNA RNA Interference Gene Knockdown
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