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Evaluation of the Efficacy of the H. pylori Protein HP-NAP as a Therapeutic Tool for Treatment of Bladder Cancer in an Orthotopic Murine Model
 

Evaluation of the Efficacy of the H. pylori Protein HP-NAP as a Therapeutic Tool for Treatment of Bladder Cancer in an Orthotopic Murine Model

Article DOI: 10.3791/52743-v • 06:12 min • May 29th, 2015
May 29th, 2015 •
1, 1, 2, 1
1Department of Biology, University of Padua, 2Department of Medical Diagnostic Sciences & Special Therapies, University of Padua

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Automatic Translation

Here the method to establish a syngeneic mouse model of orthotopic bladder tumour to evaluate the anti-tumour efficacy of the bacterial protein HP-NAP is described.

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H. Pylori Protein HP-NAP Therapeutic Tool Treatment Bladder Cancer Orthotopic Murine Model Bacillus Calmette-Guérin (BCG) Non-muscle Invasive Bladder Cancer (NMIBC) Biological Response Modifiers Tumour Microenvironment Tumour Development Therapy Efficacy Bladder Cavity Female Mice Helicobacter Pylori Neutrophil Activating Protein (HP-NAP) Mucosa Urothelial Carcinoma Cell Line MB49 Urethral Catheterization Anti-tumour Activity Tumour Volume Necrosis Vascularization
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