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Investigating von Willebrand Factor Pathophysiology Using a Flow Chamber Model of von Willebrand Factor-platelet String Formation
 

Investigating von Willebrand Factor Pathophysiology Using a Flow Chamber Model of von Willebrand Factor-platelet String Formation

Article DOI: 10.3791/55917-v • 08:30 min • August 14th, 2017
August 14th, 2017 •
1, 1, 2, 1, 1
1Department of Pathology and Molecular Medicine, Queen's University, 2Department of Medicine, Queen's University

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Automatic Translation

In this paper, we describe a method to assess endothelial von Willebrand factor release and the subsequent platelet capture under fluid shear stress in response to inflammatory stimuli using an in vitro flow chamber system.

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Keywords: Von Willebrand Factor VWF-platelet String Formation Flow Chamber Model Collagen Endothelial Cells Platelets Secretagogues In Vitro Microscopy Syringe Pump
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