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成年斑马鱼脑 Amyloid-β42毒性和神经的模型研究
 
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成年斑马鱼脑 Amyloid-β42毒性和神经的模型研究

Article DOI: 10.3791/56014-v • 10:01 min • October 25th, 2017
October 25th, 2017 •
1, 2, 1, 1, 3, 2, 1,3
1German Centre for Neurodegenerative Diseases (DZNE) Dresden within Helmholtz Association, 2B CUBE, Center for Molecular Bioengineering, Technische Universität Dresden, 3Center for Regenerative Therapies Dresden (CRTD), TU Dresden

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本协议描述了单体 amyloid-β42肽在成年斑马鱼中产生淀粉样毒性的合成、表征和注射, 以建立阿尔茨海默病模型, 随后进行组织学分析和检测聚合.

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神经科学 问题 128 淀粉样β42 斑马鱼 神经 脑室微注射 阿尔茨海默病 固相多肽合成
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