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A Method to Define the Effects of Environmental Enrichment on Colon Microbiome Biodiversity in a Mouse Colon Tumor Model
 

A Method to Define the Effects of Environmental Enrichment on Colon Microbiome Biodiversity in a Mouse Colon Tumor Model

Article DOI: 10.3791/57182-v • 08:14 min • February 28th, 2018
February 28th, 2018 •
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1Division of Gastroenterology, Hepatology, and Nutrition, Department of Internal Medicine, University of Utah, 2Huntsman Cancer Institute, University of Utah

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Environmental Enrichment (EE) is an animal housing environment that is used to reveal mechanisms that underlie the connections between lifestyle, stress, and disease. This protocol describes a procedure that uses a mouse model of colon tumorigenesis and EE to specifically define alterations in microbiota biodiversity that may impact animal mortality.

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Keywords: Environmental Enrichment Colon Microbiome Colon Tumor Model Microbiome Normalization Experimental Reproducibility Animal Stress Reduction Breeding Pup Rearing Stool Collection
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