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Optogenetisk fasövergång av TDP-43 i spinalmotoriska nervceller av zebrafisk larver
 
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Optogenetisk fasövergång av TDP-43 i spinalmotoriska nervceller av zebrafisk larver

Article DOI: 10.3791/62932-v • 07:14 min • February 25th, 2022
February 25th, 2022 •
1, 1, 2,3
1Department of Chemical Biology, Tokyo Medical University, 2Division of Molecular and Developmental Biology, National Institute of Genetics, 3Department of Genetics, Graduate University for Advanced Studies (SOKENDAI)

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Vi beskriver ett protokoll för att inducera fas övergång av TAR DNA-bindande protein 43 (TDP-43) med ljus i spinal motor nervceller med zebrafisk som modell.

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Neurovetenskap nummer 180 neurodegenerativ sjukdom ALS optoDroplet system Cryptochrome 2 TDP-43 zebrafisk spinal motor neuron, mnr2b BAC transgenes
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