/

/

慢性结肠炎相关结肠直肠癌的肿瘤切除术模型，通过卡卡贴片的精确定位

JoVE Journal
Medicine
Author Produced

A subscription to JoVE is required to view this content. Sign in or start your free trial.

JoVE Journal Medicine

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Please note that all translations are automatically generated. Click here for the English version.

慢性结肠炎相关结肠直肠癌的肿瘤切除术模型，通过卡卡贴片的精确定位

DOI:

10.3791/59921-v

•

00:08 min

•

August 24, 2019

•

Yaguang Li, Junhong Liu³, Gaixia Liu, Zhenhong Pan³, Mingxia Zhang, Yao Ma, Qingxia Wei⁵, Hongping Xia⁶, Rui Xue Zhang², Junjun She

¹Department of General Surgery, The First Affiliated Hospital,Xi’an Jiaotong University, ²Institute of Medical Research,Northwestern Polytechnical University, ³School of Life Sciences,Northwestern Polytechnical University, ⁴Department of Medicine,Xi’an Jiaotong University, ⁵Princess Margaret Cancer Center,University of Health Network, ⁶Department of Pathology,Nanjing Medical University

Chapters

00:00Title
01:11Mice Appendectomy
05:11Induction of Colitis-associated Colorectal Cancer with Azoxymethane (AOM) and Dextran Sodium Sulfate (DSS)
06:36Results
07:57Conclusion

Summary

Automatic Translation

提出的协议描述了在小鼠中插入附录（caecal贴片）的方便手术去除，然后是炎症性肠病相关结肠直肠癌的诱导。这种鼠尾切除术模型能够研究附录在人类胃肠道疾病发病机制中的生物学作用。

Tags

Keywords: Murine Appendectomy Caecal Patch Chronic Colitis Colorectal Cancer Gastrointestinal Disease Appendix Function Surgical Procedure Mouse Model Caecum Abdomen Incision Mesenteric Blood Vessels Caecal Stump Suture

Article

Embed

ADD TO PLAYLIST

Usage Statistics

Related Videos

一个小鼠膀胱癌原位模型

建模结肠炎相关的癌症与氧化偶氮甲烷（AOM）和葡聚糖硫酸钠（DSS）

灵活的结肠镜检查在小鼠使用经过验证的内镜评分系统来评估结肠炎和结肠直肠肿瘤的严重程度

人类前列腺癌转移的原位小鼠模型

在结直肠癌细胞的三维模型的入侵肿瘤微环境的分子剖析和<em>体外</em>成纤维细胞

本地化识别，切除脂肪小鼠油库，并

股动脉线损伤的小鼠模型的血管周围给药补丁植入

心肌顿抑相关的小鼠离体心脏模型心脏停搏

人前列腺癌的临床前原位小鼠模型

通过轻型显微镜对小鼠急性心肌炎模型中白细胞浸润的定量可视化

Read Article