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1Department of General Surgery, The First Affiliated Hospital,Xi’an Jiaotong University, 2Institute of Medical Research,Northwestern Polytechnical University, 3School of Life Sciences,Northwestern Polytechnical University, 4Department of Medicine,Xi’an Jiaotong University, 5Princess Margaret Cancer Center,University of Health Network, 6Department of Pathology,Nanjing Medical University
Chapters
- 00:00Title
- 01:11Mice Appendectomy
- 05:11Induction of Colitis-associated Colorectal Cancer with Azoxymethane (AOM) and Dextran Sodium Sulfate (DSS)
- 06:36Results
- 07:57Conclusion
Il protocollo presentato descrive una facile rimozione chirurgica dell'appendice (patch caecale) in un topo seguita dall'induzione del cancro colorettale associato alla malattia intestinale infiammatoria. Questo modello di appendicosa murina consente lo studio del ruolo biologico dell'appendice nella patogenesi della malattia gastrointestinale umana.
