Journal
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Indução da inflamação da superfície ocular e coleta de tecidos envolvidos
JoVE Journal
Immunology and Infection
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JoVE Journal Immunology and Infection
Induction of Ocular Surface Inflammation and Collection of Involved Tissues
DOI:

06:38 min

August 04, 2022

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Chapters

  • 00:04Introduction
  • 00:52Induction of Murine Ocular Surface Inflammation and Collection of Ocular Exudates
  • 01:54Excision of Ocular Surface Tissues from the Euthanized Mouse
  • 03:30Documentation of Meibomian Gland (MG) Obstruction and Trans-Illumination of Eyelids (MG Morphology)
  • 04:08Results: Morphological and Histopathological Features of MG Dysfunction and Investigation of Topical and Systemic Anti-Inflammatory Interventions
  • 05:59Conclusion

Summary

Automatic Translation

A inflamação da superfície ocular prejudica os tecidos da superfície ocular e compromete as funções vitais do olho. O presente protocolo descreve um método para induzir inflamação ocular e coletar tecidos comprometidos em um modelo de camundongo de disfunção da glândula de Meibomian (MGD).

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