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Subcutaneous Angiotensin II Infusion using Osmotic Pumps Induces Aortic Aneurysms in Mice
 

Subcutaneous Angiotensin II Infusion using Osmotic Pumps Induces Aortic Aneurysms in Mice

Article DOI: 10.3791/53191-v • 07:21 min • September 28th, 2015
September 28th, 2015 •
1, 1, 1, 1, 1, 2, 1
1Saha Cardiovascular Research Center, University of Kentucky, 2Department of Pharmacology and Nutritional Sciences, University of Kentucky

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Subcutaneous implantation of osmotic pumps provides a convenient approach for prolonged and consistent delivery of compounds. This approach has been used extensively to study both abdominal and thoracic aortic aneurysms in mice.

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Keywords: Subcutaneous Infusion Angiotensin II Osmotic Pumps Aortic Aneurysms Mice Hypercholesterolemia Gender Dependence Abdominal Aortic Aneurysms Thoracic Aortic Aneurysms
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