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JoVE Journal Genetics
Påvisning av Kopier nummer Endringer Bruke enkelt celle Sequencing
 
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Påvisning av Kopier nummer Endringer Bruke enkelt celle Sequencing

Article DOI: 10.3791/55143-v • 09:45 min • February 17th, 2017
February 17th, 2017 •
1,2,3, 4, 5
1Koch Institute for Integrative Cancer Research, Department of Biology, Massachusetts Institute of Technology, 2Howard Hughes Medical Institute, 3Division of Health Sciences and Technology, Harvard Medical School, 4The Barbara K. Ostrom (1978) Bioinformatics and Computing Facility in the Swanson Biotechnology Center, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 5BioMicro Center, Department of Biology, Massachusetts Institute of Technology

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Enkelt celle sekvensering er et stadig mer populært og tilgjengelig verktøy for adressering genomisk endringer i høy oppløsning. Vi tilbyr en protokoll som bruker enkelt celle sekvensering for å identifisere kopitall endringer i enkeltceller.

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Genetikk kopiantall endring fremkalle aneuploidi genomisk heterogenitet encellede hele genomet forsterkning hele genomsekvense
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