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Generation and Characterization of Right Ventricular Myocardial Infarction Induced by Permanent Ligation of the Right Coronary Artery in Mice
 

Generation and Characterization of Right Ventricular Myocardial Infarction Induced by Permanent Ligation of the Right Coronary Artery in Mice

Article DOI: 10.3791/63508-v • 10:18 min • February 1st, 2022
February 1st, 2022 •
1, 2, 2, 1, 1, 2, 3
1The First Clinical College of Dalian Medical University, 2Department of Cardiology, State Key Laboratory of Organ Failure Research, Nanfang Hospital, Southern Medical University, 3College of Pharmacy, Dalian Medical University

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There are several differences between the right and left ventricles. However, the pathophysiology of right ventricular infarction (RVI) has not been clarified. In the present protocol, a reproducible method for RVI mouse model generation is introduced, which may provide a means to explain the mechanism of RVI.

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Keywords: Right Ventricular Infarction Right Coronary Artery Ligation Mouse Model Myocardial Infarction Ischemia ECG Surgical Procedure Ultrasound Imaging
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