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Identifiering av mediatorer av T-cells Receptor signalering via Screening av kemiska hämmare bibliotek…
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Immunology and Infection
Immunology and Infection
This content is Open Access.
Identifiering av mediatorer av T-cells Receptor signalering via Screening av kemiska hämmare bibliotek
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Article
DOI:
10.3791/58946-v
•
08:49 min
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January 22nd, 2019
Identifiering av mediatorer av T-cells Receptor signalering via Screening av kemiska hämmare bibliotek
January 22nd, 2019
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Elijah W. Chen*1, Chyan Ying Ke*2,3, Joanna Brzostek*1, Nicholas R. J. Gascoigne1, Vasily Rybakin1,4
1Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, 2Singapore Immunology Network, A*STAR, 3Curiox Biosystems, 4Department of Immunobiology, Rega Institute for Medical Research, Katholieke Universiteit (KU) Leuven
* These authors contributed equally
Chapters
Summary
Please note that all translations are automatically generated.
Click here for the English version.
Detta dokument använder en flow-flödescytometri-baserad analys till skärmen bibliotek av kemiska hämmare för identifiering av hämmare och sina mål som påverkar T-cells receptor signalering. Metoderna som beskrivs här kan också utökas för hög genomströmning filmvisningar.
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Immunologi och infektion fråga 143 kaspas-3 aktivering kinashämmare bibliotek screening TCR signalering T-cells aktivering thymocyte urvalRelated Videos
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